Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD4 | P01730 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986759 | 0.91 | MAPT (0.42) | CD4F10LMNAMAPTTHRB | |
| SCHEMBL7996147 | 0.90 | LMNA (0.42) | F10LMNAMAPTTHRBTP53 | |
| SCHEMBL7999821 | 0.88 | F10 (0.48) | F10LMNAMAPTTP53SMN1; SMN2 | |
| SCHEMBL7996072 | 0.83 | LMNA (0.46) | F10LMNAMAPTCA12CA1 | |
| SCHEMBL7996075 | 0.83 | F10 (0.48) | F10LMNAMAPTCA12CA1 | |
| SCHEMBL7996149 | 0.82 | HCRTR1 (0.46) | LMNAMAPTTHRBTP53 | |
| SCHEMBL7997760 | 0.82 | MAPT (0.47) | F10LMNAMAPTTP53SMN1; SMN2 | |
| SCHEMBL7997639 | 0.81 | L3MBTL1 (0.45) | F10LMNAMAPTCA12CA1 | |
| SCHEMBL8000009 | 0.80 | LMNA (0.44) | F10LMNAMAPTTP53 | |
| SCHEMBL8003134 | 0.80 | MAPT (0.48) | F10LMNAMAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |