Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 8/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051790 | 0.85 | CYP3A4 (0.47) | MEN1KMT2ACYP3A4CASP1CSNK2A2 | |
| SCHEMBL7985593 | 0.80 | PLAU (0.31) | — | |
| SCHEMBL7988689 | 0.80 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGD | |
| SCHEMBL7986464 | 0.78 | MASP2 (0.40) | CYP3A4CSNK2A2CSNK2A1HSD17B10KDM4E | |
| SCHEMBL7992134 | 0.78 | SMN1; SMN2 (0.42) | MEN1KMT2ACASP1CSNK2A2CSNK2A1 | |
| SCHEMBL6564601 | 0.77 | ALDH1A1 (0.37) | HSD17B10ALDH1A1TSHRHPGDMAPT | |
| SCHEMBL7988767 | 0.77 | ALDH1A1 (0.35) | KMT2AMAPK1ALDH1A1TSHRHPGD | |
| SCHEMBL7988757 | 0.77 | TDP1 (0.33) | ALDH1A1 | |
| SCHEMBL7988673 | 0.77 | TSHR (0.38) | CYP3A4CASP1CSNK2A2CSNK2A1ALDH1A1 | |
| SCHEMBL482868 | 0.76 | CYP3A4 (0.55) | MEN1KMT2ACYP3A4HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |