SCHEMBL7988673

SCHEMBL7988673

COCCOC(=O)NC(=N)c1cc[c]cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
CSNK2A2 P19784 1/20 0.36
CSNK2A1 P68400 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
ALDH1A1 P00352 2/20 0.34
ABCB11 O95342 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADRA2B P18089 1/20 0.33
OPRD1 P41143 1/20 0.33
SCN5A Q14524 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
S1PR3 Q99500 1/20 0.33
POLB P06746 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7992134 0.87 SMN1; SMN2 (0.42) TSHRCSNK2A2CSNK2A1ALDH1A1TDP1
SCHEMBL7988767 0.86 ALDH1A1 (0.35) TSHRALDH1A1RAB9ANPC1HPGD
SCHEMBL7975413 0.86 SMN1; SMN2 (0.40) TSHRALDH1A1TDP1RAB9ANPC1
SCHEMBL7975316 0.85 SMN1; SMN2 (0.36) TSHRALDH1A1ABCB11CYP3A4ADRA2B
SCHEMBL7989442 0.85 CTSK (0.30)
SCHEMBL6564601 0.84 ALDH1A1 (0.37) TSHRCA12CA1CA2CA9
SCHEMBL7985659 0.84 RAB9A (0.45) TSHRALDH1A1CYP3A4TDP1RAB9A
SCHEMBL7993344 0.83 MASP2 (0.33) TSHRALDH1A1HTTMASP2LMNA
SCHEMBL7988689 0.83 ALDH1A1 (0.39) ALDH1A1POLBHPGDMASP2SMN1; SMN2
SCHEMBL7992455 0.83 NPC1 (0.44) TSHRALDH1A1CYP3A4RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed