Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999929 | 0.89 | HRH3 (0.52) | F10HRH3KDM4EMEN1ALDH1A1 | |
| SCHEMBL1651299 | 0.82 | F10 (0.55) | F10F2PLGHPNPRSS1 | |
| SCHEMBL7999713 | 0.81 | F10 (0.62) | F10F2PLG | |
| SCHEMBL7997768 | 0.80 | NPC1 (0.49) | F10HRH3LMNAF2PLG | |
| SCHEMBL7999935 | 0.79 | F10 (0.56) | F10HRH3F2PLGHPN | |
| SCHEMBL8000015 | 0.78 | F10 (0.53) | F10F2PLGHPNPRSS1 | |
| SCHEMBL7996357 | 0.77 | NPC1 (0.54) | F10HRH3ALDH1A1LMNAMAPT | |
| SCHEMBL7999871 | 0.77 | MGLL (0.48) | HRH3KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL7986943 | 0.76 | F10 (0.56) | F10HRH3F2PLGHPN | |
| SCHEMBL7986749 | 0.76 | F10 (0.56) | F10HRH3F2PLGHPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |