Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987038 | 0.89 | F10 (0.54) | HRH3DPP4LMNAALDH1A1CYP46A1 | |
| SCHEMBL7986762 | 0.85 | F10 (0.55) | HRH3DPP4ITGB3ITGA2BWDR5 | |
| SCHEMBL7996357 | 0.85 | NPC1 (0.54) | HRH3ITGB3ITGA2BTSHRLMNA | |
| SCHEMBL7074519 | 0.82 | KDM4E (0.61) | TSHRLMNAALDH1A1POLBMAPK1 | |
| Trifluoroacetic Acid SCHEMBL7997619 | 0.82 | PRSS1 (0.52) | F10F2PRSS1 | |
| SCHEMBL7996082 | 0.81 | GPR119 (0.42) | HRH3ITGB3ITGA2BLMNACYP46A1 | |
| SCHEMBL7986862 | 0.81 | F10 (0.57) | TSHRALDH1A1SMN1; SMN2WDR5F10 | |
| SCHEMBL4387744 | 0.81 | F2 (0.48) | HRH3DPP4ITGB3ITGA2BNPSR1 | |
| SCHEMBL7069417 | 0.80 | HPGD (0.68) | TSHRLMNAALDH1A1NPSR1POLB | |
| SCHEMBL7997768 | 0.79 | NPC1 (0.49) | HRH3TSHRLMNAHPGDF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |