SCHEMBL7987135

SCHEMBL7987135

COc1ccccc1C(=O)[N]S(C)(=O)=O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.49
HPGD P15428 2/20 0.46
ALDH1A1 P00352 1/20 0.46
STAT3 P40763 1/20 0.46
STS P08842 1/20 0.46
NPC1 O15118 3/20 0.45
RAB9A P51151 2/20 0.45
ABCG2 Q9UNQ0 1/20 0.45
HTT P42858 2/20 0.45
KCNK3 O14649 1/20 0.44
KCNK9 Q9NPC2 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
GAA P10253 2/20 0.43
MAPT P10636 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
HSD17B10 Q99714 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7973346 0.83 CTSD (0.50) CTSDHPGDALDH1A1STAT3STS
SCHEMBL7983681 0.82 HCRTR1 (0.53) HPGDALDH1A1HTTKCNK3KCNK9
SCHEMBL7990812 0.82 IRAK4 (0.57) ALDH1A1KCNK3KCNK9RXFP1
SCHEMBL7987106 0.80 CTSD (0.46) CTSDHPGDALDH1A1STAT3STS
SCHEMBL7991085 0.79 LMNA (0.54) ALDH1A1SMN1; SMN2MAPTTSHRRXFP1
SCHEMBL7973382 0.77 HPGD (0.42) HPGDALDH1A1NPC1RAB9AHTT
SCHEMBL7973356 0.75 CES2 (0.50) HPGDALDH1A1MAPT
SCHEMBL7991022 0.75 CES2 (0.50) HPGDALDH1A1NPC1RAB9AHTT
SCHEMBL7985043 0.75 NPC1 (0.41) HPGDALDH1A1NPC1RAB9AHTT
SCHEMBL29228929 0.75 CTSD (0.56) CTSDHPGDALDH1A1STAT3STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6331628-B1 REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2001-12-18 US disclosed