Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973403 | 0.81 | ERCC5 (0.42) | HPGDERCC5FEN1FLT1FLT4 | |
| SCHEMBL7973356 | 0.79 | CES2 (0.50) | HPGDERCC5FEN1FLT1FLT4 | |
| SCHEMBL7985043 | 0.79 | NPC1 (0.41) | HPGDHTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7991022 | 0.79 | CES2 (0.50) | HPGDERCC5FEN1HTTMAPT | |
| SCHEMBL7987828 | 0.78 | CLCN2 (0.38) | HTTALDH1A1 | |
| SCHEMBL7986988 | 0.78 | TDP1 (0.39) | ALDH1A1 | |
| SCHEMBL7987932 | 0.78 | L3MBTL1 (0.43) | HPGDCYP3A4 | |
| SCHEMBL5680618 | 0.77 | HPGD (0.48) | HPGDERCC5FEN1HTTNPC1 | |
| SCHEMBL7987135 | 0.77 | CTSD (0.49) | HPGDHTTMAPTNPC1RAB9A | |
| SCHEMBL13270166 | 0.75 | HPGD (0.47) | HPGDERCC5FEN1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |