Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988742 | 0.90 | LMNA (0.42) | TP53LMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7985420 | 0.89 | TP53 (0.42) | TP53LMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7987219 | 0.88 | ALDH1A1 (0.45) | TP53LMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7974198 | 0.88 | LMNA (0.41) | TP53LMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7985332 | 0.85 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2HPGDKMT2ARNASEL | |
| SCHEMBL7988405 | 0.85 | HPGD (0.49) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL7985609 | 0.85 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HPGDHSD17B13KMT2A | |
| SCHEMBL7986753 | 0.84 | TNKS (0.43) | TP53LMNAPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7991634 | 0.84 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HPGDHSD17B13KMT2A | |
| SCHEMBL7984682 | 0.84 | PDE4A (0.39) | TP53LMNAPOLBALDH1A1HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |