Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | UGCG | Q16739 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579633 | 0.65 | DRD3 (0.40) | GAAALDH1A1LMNAKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6983896 | 0.64 | SIGMAR1 (0.48) | GAAALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL6984000 | 0.64 | LGMN (0.40) | GAAALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL27662026 | 0.63 | MMP1 (0.45) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL6981092 | 0.62 | DRD3 (0.34) | GAALMNAKMT2AOPRM1MAPT | |
| SCHEMBL21120758 | 0.60 | KDM2B (0.66) | KDM2BALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6981668 | 0.59 | SIGMAR1 (0.38) | GAAALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL5427255 | 0.59 | MMP1 (0.39) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL8719900 | 0.58 | AKT1 (0.33) | LMNAKMT2AMAPT | |
| SCHEMBL28109125 | 0.57 | REN (0.47) | GAAALDH1A1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |