SCHEMBL7987314 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	MME	P08473	2/20	0.41

▸	PDF	Q9HBH1	2/20	0.40

▸	BIRC2	Q13490	2/20	0.37

▸	PSEN1	P49768	4/20	0.36

▸	PSEN2	P49810	4/20	0.36

▸	APH1B	Q8WW43	4/20	0.36

▸	NCSTN	Q92542	4/20	0.36

▸	APH1A	Q96BI3	4/20	0.36

▸	PSENEN	Q9NZ42	4/20	0.36

▸	MMP3	P08254	4/20	0.36

▸	MMP9	P14780	1/20	0.36

▸	MMP2	P08253	8/20	0.33

▸	MMP1	P03956	3/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7989538	0.89	PDF (0.43)	MMEPDFBIRC2MMP3MMP2
SCHEMBL7990047	0.87	PDF (0.50)	PDFBIRC2MMP3MMP2MMP1
SCHEMBL7977102	0.84	PDF (0.44)	PDFBIRC2MMP3MMP9MMP2
SCHEMBL7976169	0.84	PDF (0.44)	PDFBIRC2MMP3MMP9MMP2
SCHEMBL7990404	0.82	PSEN1 (0.37)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7990402	0.82	PSEN1 (0.37)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7990024	0.82	PDF (0.58)	PDFMMP3MMP2MMP1
SCHEMBL7986858	0.81	MMP2 (0.46)	MMP3MMP2MMP1
SCHEMBL7994397	0.81	MMP2 (0.48)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL7987308	0.81	MMP2 (0.48)	PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2001040198-A2	MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS	AVENTIS PHARMA S.A. (FR)	2001-06-07	—	—	WO	disclosed