Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.48 |
| ▸ | MMP1 | P03956 | 9/20 | 0.48 |
| ▸ | MMP3 | P08254 | 9/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 10/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 10/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 10/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 10/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 10/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 10/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994397 | 1.00 | MMP2 (0.48) | MMP2MMP1MMP3PSEN1PSEN2 | |
| SCHEMBL7986623 | 0.84 | PSEN1 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7987314 | 0.81 | MME (0.41) | MMP2MMP1MMP3PSEN1PSEN2 | |
| SCHEMBL7990047 | 0.81 | PDF (0.50) | MMP2MMP1MMP3 | |
| SCHEMBL7989538 | 0.81 | PDF (0.43) | MMP2MMP1MMP3 | |
| SCHEMBL7987311 | 0.79 | ALDH1A1 (0.34) | MMP2MMP1MMP3 | |
| SCHEMBL7976169 | 0.77 | PDF (0.44) | MMP2MMP1MMP3 | |
| SCHEMBL7990024 | 0.77 | PDF (0.58) | MMP2MMP1MMP3 | |
| SCHEMBL7977102 | 0.77 | PDF (0.44) | MMP2MMP1MMP3 | |
| SCHEMBL7986858 | 0.77 | MMP2 (0.46) | MMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |