⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169723 | 0.77 | PNMT (0.40) | — | |
| SCHEMBL9347230 | 0.71 | — | — | |
| SCHEMBL5207671 | 0.71 | HTR2A (0.36) | — | |
| SCHEMBL7981455 | 0.71 | HRH3 (0.40) | — | |
| SCHEMBL6622199 | 0.70 | MAOB (0.34) | — | |
| SCHEMBL8149465 | 0.70 | ADRB1 (0.41) | — | |
| SCHEMBL8796366 | 0.70 | IDO1 (0.42) | — | |
| SCHEMBL7985829 | 0.70 | ADRB2 (0.34) | — | |
| SCHEMBL168862 | 0.69 | ESR2 (0.55) | — | |
| SCHEMBL6619259 | 0.68 | ACP3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |