Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 3/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974026 | 0.84 | KDM4E (0.58) | L3MBTL1GAAPKMTSHRCYP11B1 | |
| SCHEMBL7975372 | 0.84 | ALDH1A1 (0.51) | GAAPKMTSHRCYP11B1CYP11B2 | |
| SCHEMBL7974034 | 0.84 | ATM (0.48) | ROCK2ROCK1MAOBKDM4CMKNK1 | |
| SCHEMBL7987690 | 0.83 | PKM (0.43) | MAOBPARP10MAPK14GAAPKM | |
| SCHEMBL5483136 | 0.83 | PKM (0.59) | GAAPKMTSHRCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7987445 | 0.82 | PKM (0.57) | GAAPKMTSHRCYP11B1CYP11B2 | |
| SCHEMBL7984239 | 0.81 | ADRA1D (0.52) | ROCK2ROCK1NR3C2SLC2A1MAPT | |
| SCHEMBL7988093 | 0.81 | FYN (0.43) | L3MBTL1GAAPKMTSHR | |
| SCHEMBL31333022 | 0.79 | ROCK2 (0.44) | ROCK2ROCK1MAOBPARP10MAPK14 | |
| SCHEMBL7987490 | 0.79 | ADORA2A (0.44) | GAAPKMTSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |