Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974478 | 0.91 | LMNA (0.43) | SMN1; SMN2LMNATSHRHTTNPSR1 | |
| SCHEMBL7985395 | 0.90 | GAA (0.43) | SMN1; SMN2LMNATSHRHTTNPSR1 | |
| SCHEMBL7985225 | 0.88 | GAA (0.48) | SMN1; SMN2HTTNPSR1NPC1RAB9A | |
| SCHEMBL7984454 | 0.86 | GAA (0.42) | TSHRGAA | |
| SCHEMBL7975267 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNATSHRALDH1A1HPGD | |
| SCHEMBL7988558 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRALDH1A1HPGDMEN1 | |
| SCHEMBL7985705 | 0.84 | CYP11B1 (0.49) | SMN1; SMN2NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL7984459 | 0.83 | NR1H2 (0.43) | SMN1; SMN2LMNAHTTALDH1A1HPGD | |
| SCHEMBL7975133 | 0.83 | ADORA2A (0.50) | SMN1; SMN2TSHRALDH1A1HPGDMAPT | |
| SCHEMBL7985071 | 0.83 | BCL2L2 (0.39) | SMN1; SMN2LMNAALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |