Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984823 | 0.87 | KAT6A (0.48) | KMT2AMEN1HTTGAAKAT6A | |
| SCHEMBL7983751 | 0.83 | KAT6A (0.45) | KMT2AMEN1HTTGAAKAT6A | |
| SCHEMBL7990723 | 0.82 | KMT2A (0.58) | KMT2AMEN1HTTKDM4ENPC1 | |
| SCHEMBL7985855 | 0.80 | KAT6A (0.52) | KMT2AMEN1HTTKAT6AKDM4E | |
| SCHEMBL6322882 | 0.78 | KMT2A (0.61) | KMT2AMEN1HTTGAAKAT6A | |
| SCHEMBL7973296 | 0.77 | KAT6A (0.55) | KMT2AMEN1KAT6A | |
| SCHEMBL592781 | 0.76 | RXRA (0.68) | KMT2AMEN1HTTGAAKAT6A | |
| SCHEMBL104194 | 0.76 | KMT2A (0.59) | KMT2AMEN1HTTGAAKAT6A | |
| SCHEMBL30184304 | 0.76 | RXRA (0.68) | KMT2AMEN1HTTGAAKAT6A | |
| SCHEMBL11798200 | 0.76 | KMT2A (0.64) | KMT2AMEN1HTTGAAKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |