Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.37 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984803 | 0.83 | MEN1 (0.38) | L3MBTL1GABRA1GABRB2CA1CA2 | |
| SCHEMBL7973353 | 0.79 | SLC6A2 (0.36) | CA12CA9KMT2ASLC6A2 | |
| SCHEMBL7973382 | 0.78 | HPGD (0.42) | CYP3A4HPGD | |
| SCHEMBL30036939 | 0.77 | GABRA1 (0.45) | GABRA1GABRB2CA1CA2BCL2 | |
| SCHEMBL7990812 | 0.77 | IRAK4 (0.57) | SLC9A1LMNAKCNK3KCNK9 | |
| SCHEMBL7985043 | 0.76 | NPC1 (0.41) | L3MBTL1CA1CA2CA12CA9 | |
| SCHEMBL7991022 | 0.76 | CES2 (0.50) | KMT2APOLBHPGDTSHR | |
| SCHEMBL7973356 | 0.76 | CES2 (0.50) | LMNAKMT2APOLBCYP1A2HPGD | |
| SCHEMBL7986988 | 0.75 | TDP1 (0.39) | CA1CA2CA9KMT2ATSHR | |
| SCHEMBL7987828 | 0.75 | CLCN2 (0.38) | GABRA1GABRB2CA12CA9SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |