Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973353 | 0.89 | SLC6A2 (0.36) | MEN1KMT2ACA12CA9SLC6A2 | |
| SCHEMBL7987932 | 0.83 | L3MBTL1 (0.43) | KMT2AL3MBTL1CA12CA1CA2 | |
| SCHEMBL7973403 | 0.79 | ERCC5 (0.42) | KMT2ANPSR1 | |
| SCHEMBL7991056 | 0.79 | NPSR1 (0.39) | CA12CA9GABRA1GABRB2NPSR1 | |
| SCHEMBL7987852 | 0.78 | IRAK4 (0.54) | — | |
| SCHEMBL7973190 | 0.78 | CES2 (0.47) | KMT2APOLB | |
| SCHEMBL7987842 | 0.78 | CES2 (0.47) | MEN1KMT2APOLB | |
| SCHEMBL7974319 | 0.78 | RAB9A (0.42) | MEN1KMT2ANPSR1POLB | |
| SCHEMBL7974560 | 0.78 | HCRTR1 (0.53) | MEN1KMT2AL3MBTL1NPSR1 | |
| SCHEMBL7973481 | 0.77 | ALDH1A1 (0.37) | CA12CA1CA2CA9NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |