SCHEMBL7988077

SCHEMBL7988077

O=S(=O)(c1[c]nccc1)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
GPR3 P46089 1/20 0.31
NAMPT P43490 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8131529 0.74 NAPRT (0.41) ALDH1A1
SCHEMBL3053466 0.73 ALDH1A1 (0.36) ALDH1A1GPR3
SCHEMBL1499360 0.71 PSIP1 (0.39)
SCHEMBL3875830 0.69 ALDH1A1 (0.33) ALDH1A1
SCHEMBL1599337 0.69 HTR6 (0.48) ALDH1A1NAMPT
SCHEMBL447764 0.68 ALDH1A1 (0.37) ALDH1A1GPR3
SCHEMBL15067261 0.67 EPAS1 (0.36) ALDH1A1
SCHEMBL2067057 0.66 ALDH1A1 (0.45) ALDH1A1
SCHEMBL15955551 0.63 NAPRT (0.57) ALDH1A1NAMPT
SCHEMBL20526138 0.61 ALDH1A1 (0.39) ALDH1A1NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3784661-A1 NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2021-03-03 EP claimed
US-6184234-B1 EFFECTIVE AGRICULTURAL PESTICIDE FOR TOBACCO, BEETS, BEANS, CABBAGE CROPS FMC CORPORATION 2001-02-06 US claimed
EP-3784661-A1 NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2021-03-03 EP disclosed
US-6184234-B1 EFFECTIVE AGRICULTURAL PESTICIDE FOR TOBACCO, BEETS, BEANS, CABBAGE CROPS FMC CORPORATION 2001-02-06 US disclosed