Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379614 | 0.74 | BRD4 (0.33) | LMNAKDM4EALDH1A1L3MBTL1TDP1 | |
| SCHEMBL7609127 | 0.73 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TAS2R14TDP1POLB | |
| SCHEMBL8115323 | 0.72 | NR3C2 (0.33) | ROCK1MCHR1 | |
| SCHEMBL7972615 | 0.70 | HRH3 (0.37) | MCHR1 | |
| SCHEMBL7989175 | 0.69 | FAAH (0.45) | LMNAGAAL3MBTL1 | |
| SCHEMBL8331046 | 0.68 | CA12 (0.50) | ROCK1CA12CA1CA2CA4 | |
| SCHEMBL8328142 | 0.68 | HDAC1 (0.47) | LMNAGAAMCHR1ALDH1A1L3MBTL1 | |
| SCHEMBL6180475 | 0.68 | L3MBTL1 (0.50) | LMNAKDM4EMCHR1ALDH1A1CA12 | |
| SCHEMBL8114784 | 0.68 | CYP19A1 (0.41) | GAA | |
| SCHEMBL7977425 | 0.68 | FAAH (0.46) | LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | claimed |