Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988537 | 1.00 | ESR1 (0.38) | ESR1SMN1; SMN2TSHRLMNACYP1A2 | |
| SCHEMBL7975292 | 0.92 | LMNA (0.36) | ESR1SMN1; SMN2TSHRLMNAMAPK1 | |
| SCHEMBL7975289 | 0.92 | LMNA (0.36) | ESR1SMN1; SMN2TSHRLMNAMAPK1 | |
| SCHEMBL7986558 | 0.85 | CTDSP1 (0.33) | ESR1SMN1; SMN2TSHRLMNACYP1A2 | |
| SCHEMBL7986561 | 0.85 | CTDSP1 (0.33) | ESR1SMN1; SMN2TSHRLMNACYP1A2 | |
| SCHEMBL7989499 | 0.75 | RAB9A (0.41) | ESR1SMN1; SMN2TSHRLMNACYP1A2 | |
| SCHEMBL7989497 | 0.75 | RAB9A (0.41) | ESR1SMN1; SMN2TSHRLMNACYP1A2 | |
| SCHEMBL7985779 | 0.75 | PKM (0.33) | — | |
| SCHEMBL7988764 | 0.75 | PKM (0.33) | — | |
| SCHEMBL131778 | 0.74 | ESR1 (0.67) | ESR1SMN1; SMN2TSHRLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |