SCHEMBL7989497

SCHEMBL7989497

CCCCOC(=O)/N=C(/NC(=O)OCCCC)c1cc[c]cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.41
SMN1; SMN2 Q16637 9/20 0.41
NPC1 O15118 8/20 0.41
CASP1 P29466 1/20 0.41
HPGD P15428 7/20 0.40
LMNA P02545 3/20 0.40
L3MBTL1 Q9Y468 4/20 0.39
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPK1 P28482 2/20 0.39
MAPT P10636 2/20 0.39
MCL1 Q07820 1/20 0.39
CYP1A2 P05177 6/20 0.38
CYP2C19 P33261 6/20 0.38
CYP2C9 P11712 3/20 0.38
TSHR P16473 3/20 0.38
ESR1 P03372 1/20 0.38
CYP2D6 P10635 1/20 0.38
NR1H2 P55055 1/20 0.38
RNASEL Q05823 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7989499 1.00 RAB9A (0.41) RAB9ASMN1; SMN2NPC1CASP1HPGD
SCHEMBL7992070 0.92 ALDH1A1 (0.39) RAB9ASMN1; SMN2NPC1CASP1HPGD
SCHEMBL7992071 0.92 ALDH1A1 (0.39) RAB9ASMN1; SMN2NPC1CASP1HPGD
SCHEMBL7975371 0.84 CYP1A2 (0.38) RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E
SCHEMBL7975368 0.84 CYP1A2 (0.38) RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E
SCHEMBL7985659 0.79 RAB9A (0.45) RAB9ASMN1; SMN2NPC1CASP1HPGD
SCHEMBL7988535 0.75 ESR1 (0.38) RAB9ASMN1; SMN2NPC1CASP1HPGD
SCHEMBL7988537 0.75 ESR1 (0.38) RAB9ASMN1; SMN2NPC1CASP1HPGD
SCHEMBL7700375 0.75 RAB9A (0.38) RAB9ASMN1; SMN2NPC1CASP1HPGD
SCHEMBL7974738 0.75 PKM (0.34) HPGDLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed