Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985794 | 0.94 | PARN (0.46) | GRIN1GRIN2BMKNK1MKNK2PARN | |
| SCHEMBL7991676 | 0.92 | ACP1 (0.43) | GRIN1GRIN2BMKNK1MKNK2PARN | |
| SCHEMBL7985266 | 0.92 | CNOT7 (0.43) | GRIN1GRIN2BMKNK1MKNK2PARN | |
| SCHEMBL7988570 | 0.91 | HPGD (0.47) | GRIN1GRIN2BPARNCNOT7ACP1 | |
| SCHEMBL7988820 | 0.91 | MAPK1 (0.48) | GRIN1GRIN2BMKNK1MKNK2PARN | |
| SCHEMBL7974508 | 0.90 | CNOT7 (0.51) | PARNCNOT7ADORA2BACP1ALDH1A1 | |
| SCHEMBL7988736 | 0.89 | ACP1 (0.45) | GRIN1GRIN2BPARNCNOT7MAPK1 | |
| SCHEMBL7984283 | 0.89 | CNOT7 (0.43) | PARNCNOT7ACP1ALDH1A1MAPT | |
| SCHEMBL7985302 | 0.89 | ROCK2 (0.41) | GRIN1GRIN2BMKNK1MKNK2PARN | |
| SCHEMBL7988752 | 0.88 | TP53 (0.48) | GRIN1GRIN2BMAPK1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |