Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 1/20 | 0.45 |
| ▸ | GRK2 | P25098 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | GRK5 | P34947 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974316 | 0.91 | TP53 (0.48) | TP53RXFP1GRIN1GRIN2BCYP1A2 | |
| SCHEMBL7974021 | 0.91 | TP53 (0.51) | TP53RXFP1CYP1A2CYP3A4LMNA | |
| SCHEMBL7974195 | 0.90 | GAA (0.48) | TP53RXFP1GRIN1GRIN2BCYP1A2 | |
| SCHEMBL7985852 | 0.90 | TP53 (0.52) | TP53RXFP1LMNAROCK1AURKA | |
| SCHEMBL7985580 | 0.90 | HPGD (0.49) | TP53RXFP1GRIN1GRIN2BCYP1A2 | |
| SCHEMBL7989314 | 0.89 | ROCK2 (0.55) | TP53RXFP1ROCK1AURKAPRKCB | |
| SCHEMBL7988644 | 0.88 | GRIN1 (0.42) | GRIN1GRIN2BALDH1A1MAPK1ROCK1 | |
| SCHEMBL7988570 | 0.87 | HPGD (0.47) | TP53GRIN1GRIN2BCYP1A2CYP3A4 | |
| SCHEMBL7985655 | 0.86 | TP53 (0.48) | TP53RXFP1ROCK1AURKAPRKCB | |
| SCHEMBL7985875 | 0.86 | TP53 (0.48) | TP53RXFP1GRIN1GRIN2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |