Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973628 | 0.90 | SMN1; SMN2 (0.48) | CNOT7SMN1; SMN2GLAHTTUBE2N | |
| SCHEMBL7974289 | 0.90 | CNOT7 (0.53) | CNOT7NPY5RSMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL8056886 | 0.89 | SMN1; SMN2 (0.46) | CNOT7SMN1; SMN2GLAHTTUBE2N | |
| SCHEMBL7988669 | 0.89 | PARN (0.48) | CNOT7SMN1; SMN2GLAHTTUBE2N | |
| SCHEMBL7985337 | 0.88 | CNOT7 (0.48) | CNOT7GRIN1GRIN2BROCK2 | |
| SCHEMBL7988938 | 0.88 | CNOT7 (0.48) | CNOT7GRIN1GRIN2BNPY5RSMN1; SMN2 | |
| SCHEMBL7991568 | 0.86 | SMN1; SMN2 (0.45) | CNOT7SMN1; SMN2GLAHTTUBE2N | |
| SCHEMBL7987437 | 0.86 | ROCK2 (0.57) | CNOT7NPY5RSMN1; SMN2HTTROCK2 | |
| SCHEMBL7974015 | 0.86 | PARN (0.49) | CNOT7SMN1; SMN2GLAHTTUBE2N | |
| SCHEMBL7991647 | 0.85 | SMN1; SMN2 (0.44) | CNOT7GRIN1GRIN2BSMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |