Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991676 | 0.90 | ACP1 (0.43) | CNOT7GRIN1GRIN2BROCK2ROCK1 | |
| SCHEMBL7989422 | 0.89 | CNOT7 (0.47) | CNOT7GRIN1GRIN2BCYP11B1CLK1 | |
| SCHEMBL7985266 | 0.89 | CNOT7 (0.43) | CNOT7GRIN1GRIN2BCYP11B1CDK9 | |
| SCHEMBL7985794 | 0.89 | PARN (0.46) | CNOT7GRIN1GRIN2BCYP11B1CDK9 | |
| SCHEMBL7988938 | 0.88 | CNOT7 (0.48) | CNOT7GRIN1GRIN2BCYP11B1ROCK2 | |
| SCHEMBL7988666 | 0.88 | CNOT7 (0.48) | CNOT7GRIN1GRIN2BROCK2 | |
| SCHEMBL7974289 | 0.88 | CNOT7 (0.53) | CNOT7CLK1DYRK1A | |
| SCHEMBL7988644 | 0.87 | GRIN1 (0.42) | CNOT7GRIN1GRIN2BROCK2ROCK1 | |
| SCHEMBL7985302 | 0.86 | ROCK2 (0.41) | CNOT7GRIN1GRIN2BCDK9ROCK2 | |
| SCHEMBL7987437 | 0.86 | ROCK2 (0.57) | CNOT7ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |