Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974270 | 0.92 | ALDH1A1 (0.46) | CNOT7ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL7985238 | 0.90 | LMNA (0.43) | CNOT7ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL7988938 | 0.89 | CNOT7 (0.48) | CNOT7ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL7988570 | 0.89 | HPGD (0.47) | CNOT7ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL7985266 | 0.88 | CNOT7 (0.43) | CNOT7CYP11B1CYP11B2MAPK14KDM4E | |
| SCHEMBL8056886 | 0.88 | SMN1; SMN2 (0.46) | CNOT7HPGDHTTSMN1; SMN2MAPK14 | |
| SCHEMBL7985827 | 0.87 | CNOT7 (0.49) | CNOT7ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL7989314 | 0.87 | ROCK2 (0.55) | MAPK14KDM4EROCK2ROCK1 | |
| SCHEMBL7974444 | 0.87 | CNOT7 (0.52) | CNOT7ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7991561 | 0.87 | HPGD (0.43) | CNOT7ALDH1A1CYP11B1CYP11B2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |