Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988736 | 0.92 | ACP1 (0.45) | CNOT7PARNACP1LMNAKDM4E | |
| SCHEMBL7985302 | 0.91 | ROCK2 (0.41) | CNOT7PARNACP1PNPEGFR | |
| SCHEMBL7984663 | 0.90 | CNOT7 (0.49) | CNOT7PARNPNPKDM4EALDH1A1 | |
| SCHEMBL7988784 | 0.90 | MAPK1 (0.43) | CNOT7PARNACP1LMNASMN1; SMN2 | |
| SCHEMBL7984427 | 0.90 | HPGD (0.44) | CNOT7PARNACP1PNPLMNA | |
| Hydrochloric Acid SCHEMBL7987663 | 0.89 | CNOT7 (0.48) | CNOT7PARNPNPKDM4EALDH1A1 | |
| SCHEMBL7985619 | 0.89 | CNOT7 (0.41) | CNOT7PARNACP1EGFRLMNA | |
| SCHEMBL7986522 | 0.88 | CNOT7 (0.48) | CNOT7PARNACP1PNPLMNA | |
| SCHEMBL7991403 | 0.87 | ABCC8 (0.43) | CNOT7PARNPNPKDM4EALDH1A1 | |
| SCHEMBL7984283 | 0.87 | CNOT7 (0.43) | CNOT7PARNACP1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |