Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.41 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991638 | 0.91 | GRIN1 (0.42) | CNOT7PARNIDO1TDO2ACP1 | |
| SCHEMBL7988736 | 0.91 | ACP1 (0.45) | CNOT7PARNACP1HDAC1HDAC6 | |
| SCHEMBL7985342 | 0.91 | CNOT7 (0.51) | CNOT7PARNALDH1A1 | |
| SCHEMBL7985568 | 0.90 | CNOT7 (0.41) | CNOT7PARNACP1HSD17B13HDAC1 | |
| SCHEMBL7988784 | 0.89 | MAPK1 (0.43) | CNOT7PARNIDO1ACP1LMNA | |
| SCHEMBL7974418 | 0.89 | CNOT7 (0.39) | CNOT7PARNACP1EGFRLMNA | |
| SCHEMBL7974282 | 0.87 | ABCC8 (0.43) | CNOT7PARNHSD17B13HDAC1HDAC6 | |
| SCHEMBL7986522 | 0.87 | CNOT7 (0.48) | CNOT7PARNACP1LMNAKDM4E | |
| SCHEMBL7991647 | 0.87 | SMN1; SMN2 (0.44) | CNOT7PARNACP1PIK3CDPIK3CB | |
| SCHEMBL7984283 | 0.86 | CNOT7 (0.43) | CNOT7PARNACP1METLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |