Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985291 | 0.93 | CNOT7 (0.54) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7985494 | 0.86 | CNOT7 (0.52) | CNOT7LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL7984244 | 0.86 | CNOT7 (0.60) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7991656 | 0.85 | CNOT7 (0.55) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7988799 | 0.83 | LMNA (0.54) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7974048 | 0.82 | CNOT7 (0.53) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7985605 | 0.82 | CNOT7 (0.54) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7984493 | 0.82 | CNOT7 (0.54) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7984469 | 0.82 | CNOT7 (0.54) | CNOT7LMNAKDM4EPOLBMAPK1 | |
| SCHEMBL7974620 | 0.79 | CNOT7 (0.58) | CNOT7LMNAKDM4EPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |