Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 5/20 | 0.52 |
| ▸ | PARN | O95453 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974054 | 0.91 | EGLN1 (0.44) | CNOT7PARNALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7991535 | 0.91 | CNOT7 (0.43) | CNOT7PARNALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7992180 | 0.90 | SMN1; SMN2 (0.45) | CNOT7PARNSMN1; SMN2NPC1HTT | |
| SCHEMBL7985291 | 0.88 | CNOT7 (0.54) | CNOT7PARNALDH1A1NPC1LMNA | |
| SCHEMBL7991661 | 0.88 | ABCC8 (0.45) | CNOT7PARNALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7974009 | 0.88 | METAP2 (0.41) | CNOT7PARNNPC1RAB9AMETAP2 | |
| SCHEMBL7991792 | 0.88 | ALDH1A1 (0.44) | CNOT7PARNALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7988804 | 0.86 | CNOT7 (0.55) | CNOT7PARNALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7985461 | 0.86 | TP53 (0.48) | NPC1LMNAGAARAB9ARXFP1 | |
| SCHEMBL7975271 | 0.85 | CNOT7 (0.56) | CNOT7PARNPNPALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |