Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.42 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455306 | 0.87 | NR3C1 (0.44) | LPAR1LPAR5SCN4APARP10NR3C1 | |
| SCHEMBL7460324 | 0.77 | LTA4H (0.42) | SCN4APARP10CARM1PRMT6PNLIP | |
| SCHEMBL7459213 | 0.76 | CARM1 (0.48) | SCN4APARP10NR3C1CARM1PRMT6 | |
| SCHEMBL4991862 | 0.73 | CARM1 (0.48) | SCN4APARP10NR3C1CARM1PRMT6 | |
| SCHEMBL14656214 | 0.73 | TTR (0.51) | SCN4ANR3C1CARM1PRMT6PNLIP | |
| SCHEMBL7990379 | 0.73 | FFAR1 (0.57) | LPAR1LPAR5PARP10OPRM1OPRD1 | |
| SCHEMBL14662185 | 0.72 | PPARG (0.54) | CARM1PRMT6 | |
| SCHEMBL5569145 | 0.71 | HSPB1 (0.48) | SCN4ANR3C1CARM1PRMT6PNLIP | |
| SCHEMBL3024115 | 0.71 | PARP10 (0.67) | SCN4APARP10PNLIPMETHSPB1 | |
| SCHEMBL22756319 | 0.71 | SCN4A (0.47) | LPAR1LPAR5SCN4APARP10NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281211-B1 | TREATING A DISORDER RESPONSIVE TO THE BLOCKADE OF SODIUM CHANNELS | EURO-CELTIQUE S.A. (LU) | 2001-08-28 | — | — | US | disclosed |