Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PNLIP | P16233 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989071 | 0.87 | LPAR1 (0.42) | NR3C1SCN4APARP10LPAR1LPAR5 | |
| SCHEMBL7459213 | 0.78 | CARM1 (0.48) | NR3C1SCN4APARP10CARM1PRMT6 | |
| SCHEMBL4991862 | 0.75 | CARM1 (0.48) | NR3C1SCN4APARP10CARM1PRMT6 | |
| SCHEMBL14656214 | 0.75 | TTR (0.51) | NR3C1SCN4ACARM1PRMT6PNLIP | |
| SCHEMBL14662185 | 0.74 | PPARG (0.54) | CARM1PRMT6 | |
| SCHEMBL7460324 | 0.73 | LTA4H (0.42) | SCN4APARP10CARM1PRMT6PNLIP | |
| SCHEMBL5569145 | 0.73 | HSPB1 (0.48) | NR3C1SCN4ACARM1PRMT6PNLIP | |
| SCHEMBL3024115 | 0.73 | PARP10 (0.67) | SCN4APARP10PNLIPHSPB1MET | |
| SCHEMBL7996091 | 0.73 | FAAH (0.47) | NR3C1SCN4APARP10CARM1PRMT6 | |
| SCHEMBL11990070 | 0.72 | HSPB1 (0.46) | CARM1PRMT6HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020037926-A1 | Sodium channel blocker compositions and the use thereof | PURDUE PHARMA LTD. | 2002-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037926-A1 | Sodium channel blocker compositions and the use thereof | CACNA1B, CACNB2, CACNA1C | NR3C1 2955/4885SCN4A 27/4885PARP10 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.