Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.84 |
| ▸ | HTR1A | P08908 | 4/20 | 0.71 |
| ▸ | DRD2 | P14416 | 2/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373313 | 0.91 | SIGMAR1 (1.00) | SIGMAR1HTR1ADRD2KCNH2HTR7 | |
| SCHEMBL6509439 | 0.84 | DRD2 (1.00) | SIGMAR1HTR1ADRD2KCNH2MAPT | |
| SCHEMBL9373469 | 0.83 | SIGMAR1 (1.00) | SIGMAR1HTR1AKCNH2SLC6A2SLC6A4 | |
| SCHEMBL10861239 | 0.82 | HTR1A (0.72) | SIGMAR1HTR1ADRD2HTR7MAPT | |
| Hydrochloric Acid SCHEMBL1299006 | 0.82 | SIGMAR1 (0.71) | SIGMAR1 | |
| SCHEMBL7995650 | 0.82 | HTR1A (0.71) | SIGMAR1HTR1ADRD2KCNH2HTR7 | |
| Hydrochloric Acid SCHEMBL8092298 | 0.82 | SIGMAR1 (0.97) | SIGMAR1HTR1AKCNH2HTR7SLC6A2 | |
| SCHEMBL9374413 | 0.80 | SIGMAR1 (0.76) | SIGMAR1HTR1ADRD2KCNH2HTR7 | |
| SCHEMBL1334024 | 0.79 | LMNA (0.69) | SIGMAR1HTR1AKCNH2HTR7SLC6A2 | |
| SCHEMBL28742033 | 0.78 | SIGMAR1 (0.56) | SIGMAR1HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | claimed |