Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989427 | 1.00 | MMP9 (0.51) | MMP9MMP8PPARGMAOBMME | |
| SCHEMBL7977831 | 0.87 | MMP2 (0.44) | MMP9MMP8PPARGMAOBMME | |
| SCHEMBL7977828 | 0.87 | MMP2 (0.44) | MMP9MMP8PPARGMAOBMME | |
| SCHEMBL7975785 | 0.85 | MAOB (0.47) | PPARGMAOBKDM4ENPC1ALDH1A1 | |
| SCHEMBL7975789 | 0.85 | MAOB (0.47) | PPARGMAOBKDM4ENPC1ALDH1A1 | |
| SCHEMBL7989433 | 0.80 | KDM4E (0.43) | KDM4ENPC1ALDH1A1RAB9ALTB4R | |
| SCHEMBL7986414 | 0.79 | MEN1 (0.40) | PPARGNPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL7986417 | 0.79 | MEN1 (0.40) | PPARGNPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL7993920 | 0.76 | ALDH1A1 (0.39) | ACENPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL7993921 | 0.76 | ALDH1A1 (0.39) | ACENPC1ALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |