Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.44 |
| ▸ | MMP1 | P03956 | 7/20 | 0.44 |
| ▸ | MMP3 | P08254 | 7/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977831 | 1.00 | MMP2 (0.44) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL7989431 | 0.87 | MMP9 (0.51) | MMP9MMP8MMEACECPA1 | |
| SCHEMBL7989427 | 0.87 | MMP9 (0.51) | MMP9MMP8MMEACECPA1 | |
| SCHEMBL7987529 | 0.85 | MMP3 (0.42) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL7989516 | 0.85 | MMP3 (0.42) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL7985989 | 0.83 | FFAR1 (0.39) | MAOB | |
| SCHEMBL7975672 | 0.82 | MMP2 (0.40) | MMP2MMP1MMP3MMP8ACE | |
| SCHEMBL7977132 | 0.82 | MMP2 (0.40) | MMP2MMP1MMP3MMP8ACE | |
| SCHEMBL7986858 | 0.81 | MMP2 (0.46) | MMP2MMP1MMP3 | |
| SCHEMBL7975565 | 0.81 | FOLH1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |