Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 2/20 | 0.34 | |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 5/20 | 0.30 |
| ▸ | MMP3 | P08254 | 5/20 | 0.30 |
| ▸ | MMP1 | P03956 | 3/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
| ▸ | MMP7 | P09237 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986950 | 0.92 | EPHX2 (0.39) | PDFEPHX2ABCC4MAPT | |
| SCHEMBL7987318 | 0.87 | PDF (0.33) | PDFITGB3ITGA2B | |
| SCHEMBL7976171 | 0.84 | PDF (0.33) | PDFITGB3ITGA2B | |
| SCHEMBL7990027 | 0.83 | PDF (0.35) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL7987210 | 0.81 | PDF (0.33) | PDFEPHX2ABCC4MAPTITGB3 | |
| SCHEMBL7986215 | 0.79 | EPHX2 (0.38) | EPHX2ABCC4MAPTTSHR | |
| SCHEMBL7986860 | 0.78 | MMP2 (0.38) | MMP2MMP3ITGB3 | |
| SCHEMBL7989538 | 0.77 | PDF (0.43) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL7976169 | 0.75 | PDF (0.44) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL7977102 | 0.75 | PDF (0.44) | PDFMMP2MMP3MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |