Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.38 |
| ▸ | MMP3 | P08254 | 9/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993925 | 0.85 | CYP2C19 (0.39) | KDM4A | |
| SCHEMBL7993697 | 0.78 | KMT2A (0.40) | MMP2 | |
| SCHEMBL7985989 | 0.78 | FFAR1 (0.39) | — | |
| SCHEMBL7989540 | 0.78 | PDF (0.34) | MMP2MMP3ITGB3 | |
| SCHEMBL7986630 | 0.78 | TAAR1 (0.33) | ITGB3 | |
| SCHEMBL7987318 | 0.77 | PDF (0.33) | ITGB3 | |
| SCHEMBL7986858 | 0.77 | MMP2 (0.46) | MMP2MMP3 | |
| SCHEMBL7976197 | 0.76 | CYP26A1 (0.37) | MMP2MMP3 | |
| SCHEMBL7976195 | 0.76 | CYP26A1 (0.37) | MMP2MMP3 | |
| SCHEMBL7986950 | 0.75 | EPHX2 (0.39) | KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |