Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | ATP4A | P20648 | 2/20 | 0.45 |
| ▸ | ATP4B | P51164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16345874 | 0.83 | GSTP1 (0.48) | KMT2A | |
| SCHEMBL8013638 | 0.81 | LTA4H (0.62) | LTA4HALDH1A1KDM4E | |
| SCHEMBL7348121 | 0.79 | TBXAS1 (0.64) | LTA4HHMOX1KMT2ATBXAS1CYP19A1 | |
| SCHEMBL7132156 | 0.71 | LTA4H (1.00) | LTA4HHMOX1KMT2ATBXAS1ALDH1A1 | |
| SCHEMBL10370478 | 0.71 | TBXAS1 (1.00) | LTA4HKMT2ATBXAS1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9996050 | 0.70 | TBXAS1 (0.97) | LTA4HKMT2ATBXAS1ALDH1A1KDM4E | |
| SCHEMBL7877011 | 0.69 | QPCT (0.66) | LTA4HHMOX1KMT2ATBXAS1CYP19A1 | |
| SCHEMBL5759785 | 0.68 | HMOX1 (0.85) | LTA4HHMOX1KMT2ATBXAS1CYP19A1 | |
| SCHEMBL8685441 | 0.68 | TBXAS1 (0.70) | LTA4HKMT2ATBXAS1CYP19A1ALDH1A1 | |
| SCHEMBL7477480 | 0.68 | HMOX1 (0.75) | LTA4HHMOX1KMT2ATBXAS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284756-B1 | ANTICOAGULANT | ELI LILLY AND COMPANY | 2001-09-04 | — | — | US | disclosed |