SCHEMBL7989608

SCHEMBL7989608

Cc1ccccc1COC[C@@H](OCc1ccc(F)cc1)[C@@H](O)[C@H](O)[C@@H](COCc1ccccc1C)OCc1ccc(F)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
PKM P14618 1/20 0.36
POLB P06746 4/20 0.35
KDM4E B2RXH2 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
PTGER1 P34995 1/20 0.35
PTGER4 P35408 1/20 0.35
PTGER3 P43115 1/20 0.35
PTGER2 P43116 1/20 0.35
AR P10275 1/20 0.34
CHRM3 P20309 1/20 0.34
HSP90AA1 P07900 1/20 0.34
PLA2G1B P04054 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TRPV6 Q9H1D0 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7987648 0.87 HSP90AA1 (0.39) ALDH1A1PKMKDM4ETDP1CHRM3
SCHEMBL7509426 0.86 MPO (0.41) ALDH1A1PKMPOLBKDM4ETDP1
SCHEMBL7987303 0.85 HSP90AA1 (0.43) ALDH1A1PKMKDM4ETDP1CHRM3
SCHEMBL7986289 0.84 IDO1 (0.38) ALDH1A1TDP1ARL3MBTL1LMNA
SCHEMBL7510838 0.84 KDM4E (0.36) ALDH1A1PKMKDM4ETDP1PTGER1
SCHEMBL7989889 0.84 CA1 (0.47) CHRM3HSP90AA1CA1CA2CA7
SCHEMBL7509273 0.84 CA1 (0.47) CHRM3HSP90AA1CA1CA2CA7
SCHEMBL7989942 0.84 CA1 (0.47) CHRM3HSP90AA1CA1CA2CA7
SCHEMBL7447822 0.84 HSP90AA1 (0.44) KDM4ECHRM3HSP90AA1L3MBTL1CA1
SCHEMBL7992780 0.83 IDO1 (0.41) ARHSP90AA1CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313177-B1 AS ANTIVIRAL AGENTS PHARMACOR INC. (CA) 2001-11-06 US disclosed