Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451561 | 0.85 | IDO1 (0.39) | IDO1ALDH1A1MAOBL3MBTL1MAPT | |
| SCHEMBL7571942 | 0.85 | AR (0.36) | IDO1ALDH1A1MAOBARNPC1 | |
| SCHEMBL7986153 | 0.84 | LMNA (0.39) | IDO1ALDH1A1MAOBMAPTHPGD | |
| SCHEMBL7989608 | 0.84 | ALDH1A1 (0.36) | ALDH1A1RXRAARL3MBTL1MAPT | |
| SCHEMBL7989289 | 0.83 | CA1 (0.42) | IDO1ALDH1A1MAOBTSHR | |
| SCHEMBL7976011 | 0.83 | CA1 (0.45) | IDO1TSHRTACR1HTT | |
| SCHEMBL7989311 | 0.82 | CA1 (0.44) | IDO1ALDH1A1TSHRTACR1HTT | |
| SCHEMBL7989824 | 0.81 | ALDH1A1 (0.39) | IDO1ALDH1A1MAOBL3MBTL1MAPT | |
| SCHEMBL7987648 | 0.81 | HSP90AA1 (0.39) | IDO1ALDH1A1MAOBL3MBTL1LMNA | |
| SCHEMBL7508198 | 0.80 | TDP1 (0.33) | IDO1ALDH1A1MAOBRXRAHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |