Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.55 |
| ▸ | RAF1 | P04049 | 7/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.55 |
| ▸ | TEK | Q02763 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992089 | 0.83 | MAPK14 (0.62) | MAPK14RAF1MAPK13MAPK12MAPK11 | |
| SCHEMBL7995032 | 0.83 | MAPK14 (0.58) | MAPK14RAF1MAPK13MAPK12MAPK11 | |
| SCHEMBL7988468 | 0.82 | TEK (0.49) | MAPK14RAF1MAPK13MAPK12MAPK11 | |
| SCHEMBL7989925 | 0.80 | MAPK14 (0.62) | MAPK14RAF1MAPK13MAPK12MAPK11 | |
| SCHEMBL6468974 | 0.80 | MAPK14 (0.80) | MAPK14RAF1MAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL7989219 | 0.77 | RAB9A (0.50) | KDM4EPOLBNPC1ALDH1A1RAB9A | |
| SCHEMBL3917722 | 0.76 | PIN1 (0.65) | KDM4ENPC1ALDH1A1RAB9AGPR55 | |
| SCHEMBL29093221 | 0.75 | PIN1 (0.69) | KDM4EPOLBALDH1A1 | |
| SCHEMBL5198574 | 0.75 | MAPK14 (0.73) | MAPK14RAF1MAPK13MAPK12MAPK11 | |
| SCHEMBL7989339 | 0.74 | MAPK14 (0.46) | MAPK14RAF1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |