Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | IDO1 | P14902 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16566486 | 0.84 | ALDH1A1 (0.69) | KMT2AIDO1MEN1ALDH1A1MAPT | |
| SCHEMBL26991 | 0.83 | IDO1 (0.79) | KMT2AIDO1MEN1ALDH1A1MAPT | |
| SCHEMBL29481122 | 0.83 | IDO1 (0.79) | KMT2AIDO1MEN1ALDH1A1MAPT | |
| SCHEMBL5454961 | 0.82 | MAOB (0.75) | KMT2AIDO1MEN1ALDH1A1MAPT | |
| SCHEMBL13666033 | 0.82 | MEN1 (0.70) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL16566574 | 0.82 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1MAPTALOX12 | |
| SCHEMBL7989797 | 0.80 | KMT2A (0.76) | KMT2AIDO1MEN1ALDH1A1MAPT | |
| SCHEMBL16566479 | 0.80 | ALDH1A1 (0.70) | KMT2AIDO1ALDH1A1 | |
| SCHEMBL6811430 | 0.80 | MEN1 (0.71) | KMT2AIDO1MEN1ALDH1A1MAPT | |
| SCHEMBL7596527 | 0.78 | ALDH1A1 (0.68) | KMT2AIDO1MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271236-B1 | PHENYL UREAS/THIOUREAS AS INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE ENZYME, USEFUL IN TREATING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, AND VARICELLA-ZOSTER VIRUS | WYETH | 2001-08-07 | — | — | US | disclosed |