Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831528 | 0.86 | KDM4E (1.00) | KMT2AMEN1KDM4EGAANPC1 | |
| SCHEMBL11009842 | 0.81 | MEN1 (0.72) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL7691719 | 0.80 | KDM4E (0.50) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL7989801 | 0.80 | KMT2A (0.64) | KMT2AMEN1ALDH1A1MAPTALOX12 | |
| SCHEMBL16566486 | 0.80 | ALDH1A1 (0.69) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL6811419 | 0.79 | MEN1 (0.64) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL26991 | 0.79 | IDO1 (0.79) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL29481122 | 0.79 | IDO1 (0.79) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL7981202 | 0.78 | MAPK14 (0.56) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL5454961 | 0.77 | MAOB (0.75) | KMT2AMEN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271236-B1 | PHENYL UREAS/THIOUREAS AS INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE ENZYME, USEFUL IN TREATING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, AND VARICELLA-ZOSTER VIRUS | WYETH | 2001-08-07 | — | — | US | disclosed |