Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484871 | 0.86 | P2RX7 (0.42) | P2RX7LMNAARMAPTTHRA | |
| SCHEMBL7989856 | 0.83 | THRB (0.46) | P2RX7THRATHRBMEN1KMT2A | |
| SCHEMBL7480013 | 0.80 | P2RX7 (0.41) | P2RX7ARL3MBTL1THRATHRB | |
| SCHEMBL8005262 | 0.79 | THRB (0.43) | P2RX7THRATHRBMEN1KMT2A | |
| SCHEMBL7480005 | 0.79 | P2RX7 (0.39) | P2RX7ARTHRATHRBNPBWR1 | |
| SCHEMBL7998709 | 0.77 | THRB (0.43) | P2RX7THRATHRBMEN1KMT2A | |
| SCHEMBL7989892 | 0.75 | RAB9A (0.35) | LMNAKDM4EARRAB9AL3MBTL1 | |
| SCHEMBL8002841 | 0.75 | NAPRT (0.43) | LMNARAB9AL3MBTL1MAPTNAPRT | |
| SCHEMBL7481801 | 0.74 | KMT2A (0.38) | P2RX7LMNAARMAPTTHRA | |
| SCHEMBL7990339 | 0.72 | PARP1 (0.34) | RAB9AL3MBTL1MAPTNAPRTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | disclosed |