Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 3/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.46 |
| ▸ | GUSB | P08236 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991800 | 0.87 | KDM4E (0.51) | MEN1KMT2AMAPTMAPK13GCGR | |
| SCHEMBL7977756 | 0.84 | AR (0.48) | IDO1MAPTPSDALDH1A1GAA | |
| SCHEMBL7988654 | 0.84 | MMP2 (0.57) | IDO1TNKSTNKS2GUSBNLRP3 | |
| SCHEMBL7991880 | 0.83 | MAPK14 (0.60) | TNKSTNKS2PARP2MAPK13GCGR | |
| SCHEMBL7989339 | 0.83 | MAPK14 (0.46) | TNKSTNKS2GUSBPARP2PARP1 | |
| SCHEMBL7991805 | 0.83 | KDM4E (0.48) | TNKSTNKS2MEN1KMT2APARP1 | |
| SCHEMBL7977743 | 0.83 | MAPT (0.54) | IDO1TNKSTNKS2GUSBNLRP3 | |
| SCHEMBL7995032 | 0.82 | MAPK14 (0.58) | IDO1MAPTMAPK13GCGRMAPK12 | |
| SCHEMBL7989059 | 0.81 | MAPT (0.51) | TNKSTNKS2GUSBMEN1KMT2A | |
| SCHEMBL7977712 | 0.81 | MAPK14 (0.48) | TNKSTNKS2PARP2MAPTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |