Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991800 | 0.88 | KDM4E (0.51) | MAPTCYP2C19KDM4EALDH1A1MEN1 | |
| SCHEMBL7991805 | 0.87 | KDM4E (0.48) | CYP2C19KDM4EALDH1A1MEN1CYP1A2 | |
| SCHEMBL7989706 | 0.86 | TARBP2 (0.49) | MAPTKDM4EALDH1A1MEN1GLA | |
| SCHEMBL7989339 | 0.84 | MAPK14 (0.46) | CYP2C19KDM4ECYP1A2PIN1TNKS | |
| SCHEMBL7991880 | 0.84 | MAPK14 (0.60) | CYP2C19KDM4ECYP1A2PIN1TNKS | |
| SCHEMBL7995032 | 0.83 | MAPK14 (0.58) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL6467375 | 0.82 | MAPK13 (0.62) | MAPTCYP2C19KDM4EALDH1A1MEN1 | |
| SCHEMBL7989665 | 0.81 | GPR84 (0.43) | CYP2C19KDM4EALDH1A1MEN1GLA | |
| SCHEMBL7977712 | 0.81 | MAPK14 (0.48) | MAPTKDM4EGAATP53PIN1 | |
| SCHEMBL7989916 | 0.81 | IDO1 (0.50) | MAPTKDM4EALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |