Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29166026 | 0.92 | NR4A2 (0.53) | NR4A2ALDH1A1GAACYP2C19HDAC3 | |
| SCHEMBL7990104 | 0.88 | MAOA (0.56) | NR4A2ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL3383369 | 0.87 | HDAC3 (0.57) | NR4A2ALDH1A1GAACYP2C19HDAC3 | |
| SCHEMBL3386410 | 0.87 | HDAC1 (0.62) | NR4A2ALDH1A1GAACYP2C19HDAC3 | |
| SCHEMBL14565162 | 0.83 | ALDH1A1 (0.50) | NR4A2ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL26463548 | 0.83 | MAOA (0.48) | NR4A2ALDH1A1GAACYP2C19LMNA | |
| SCHEMBL5924614 | 0.83 | ALDH1A1 (0.44) | NR4A2ALDH1A1GAACYP2C19LMNA | |
| SCHEMBL28966305 | 0.81 | CES2 (0.46) | NR4A2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL28966302 | 0.81 | KMT2A (0.66) | ALDH1A1GAALMNASMN1; SMN2FFAR1 | |
| SCHEMBL31332617 | 0.79 | KMT2A (0.59) | NR4A2ALDH1A1SMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115786940-A | Gamma-sulfonyl lactonization derivative and preparation method thereof | 江西师范大学 | 2023-03-14 | — | — | CN | claimed |
| CN-113929806-B | Oil displacement agent for supercritical carbon dioxide displacement and preparation method and application thereof | 山东德仕化工有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-113929806-A | Oil displacement agent for supercritical carbon dioxide displacement and preparation method and application thereof | 山东德仕化工有限公司 | 2022-01-14 | — | — | CN | claimed |
| EP-1329497-B1 | Utilization of unsaturated esters as perfuming ingredients | FIRMENICH & CIE (CH) | 2010-12-01 | — | — | EP | claimed |
| US-4990580-A | Process for production of styrene polymers | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-02-05 | — | — | US | claimed |
| CN-118359658-A | Synthesis method of germanium substituted gamma-lactone compound | 滁州学院 | 2024-07-19 | — | — | CN | disclosed |
| CN-115786940-A | Gamma-sulfonyl lactonization derivative and preparation method thereof | 江西师范大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-113929806-B | Oil displacement agent for supercritical carbon dioxide displacement and preparation method and application thereof | 山东德仕化工有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-111848460-B | N-thioaryl benzenesulfonylimine and preparation method and application thereof | 上海交通大学 | 2022-02-22 | — | — | CN | disclosed |
| CN-113929806-A | Oil displacement agent for supercritical carbon dioxide displacement and preparation method and application thereof | 山东德仕化工有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-111217733-B | N-thiocyanobenzenesulfonylimide and preparation method and application thereof | 上海交通大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-111848460-A | N-thioaryl benzenesulfonylimine and preparation method and application thereof | 上海交通大学 | 2020-10-30 | — | — | CN | disclosed |
| WO-2007111994-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF DISORDERS ASSOCIATED WITH ER STRESS | SYNDEXA PHARMACEUTICALS CORPORATION (US) | 2007-10-04 | — | — | WO | disclosed |
| US-20070078188-A1 | Compositions comprising and methods of using norfluoxetine | CURRIE MARK G | 2007-04-05 | — | — | US | disclosed |
| US-20060122184-A1 | Cyanomethyl derivatives as cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2006-06-08 | — | — | US | disclosed |
| US-20050288336-A1 | Cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | US | disclosed |
| EP-1569954-A1 | CYANOMETHYL DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-09-07 | — | — | EP | disclosed |
| EP-1503997-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2004052921-A1 | CYANOMETHYL DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-06-24 | — | — | WO | disclosed |
| WO-2003097617-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122184-A1 | Cyanomethyl derivatives as cysteine protease inhibitors | CTSF, CTSB, CTSK | NR4A2 4834/4885ALDH1A1 3662/4885GAA 76/4885 |
| US-20050288336-A1 | Cysteine protease inhibitors | CTSF, CTSS, CTSB | NR4A2 4848/4885ALDH1A1 2872/4885GAA 88/4885 |
| US-20070078188-A1 | Compositions comprising and methods of using norfluoxetine | ALOX5, NGF, PTGER4 | NR4A2 1067/4885ALDH1A1 337/4885GAA 2962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.