Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 7/20 | 0.42 |
| ▸ | CDK7 | P50613 | 5/20 | 0.42 |
| ▸ | CCNH | P51946 | 5/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990707 | 0.94 | CDK9 (0.44) | CDK9CDK7CCNHMNAT1CCNT1 | |
| SCHEMBL7976643 | 0.92 | CDK9 (0.40) | CDK9CDK7CCNHMNAT1CCNT1 | |
| SCHEMBL7976189 | 0.91 | CCNT1 (0.40) | CDK9CDK7CCNHMNAT1CCNT1 | |
| SCHEMBL7993811 | 0.88 | KDR (0.39) | CDK9CDK7CCNHMNAT1CCNT1 | |
| SCHEMBL7990422 | 0.87 | ABL1 (0.38) | CDK9CDK7CCNHMNAT1CCNT1 | |
| SCHEMBL7994227 | 0.86 | CDK9 (0.39) | CDK9CDK7CCNHMNAT1CCNT1 | |
| SCHEMBL7987644 | 0.84 | CCNT1 (0.40) | CDK9CDK7CCNHMNAT1CCNT1 | |
| SCHEMBL7986838 | 0.84 | CCNT1 (0.40) | CDK9CDK7CCNHMNAT1CCNT1 | |
| SCHEMBL7987305 | 0.81 | CCNT1 (0.42) | CDK9CDK7CCNHMNAT1CCNT1 | |
| SCHEMBL7548474 | 0.81 | CDK7 (0.42) | CDK9CDK7CCNHMNAT1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |