Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990504 | 0.81 | MMP3 (1.00) | MMP3NPC1RAB9AMEN1CYP3A4 | |
| SCHEMBL7483747 | 0.80 | CYP3A4 (0.46) | MMP3NPC1RAB9AMEN1CYP3A4 | |
| SCHEMBL7993209 | 0.79 | MMP3 (0.79) | MMP3NPC1RAB9AMEN1CYP3A4 | |
| SCHEMBL7997018 | 0.78 | MMP3 (0.44) | MMP3CYP3A4KDM4ESMN1; SMN2MAPT | |
| SCHEMBL7996909 | 0.77 | MMP3 (1.00) | MMP3NPC1RAB9AMEN1CYP3A4 | |
| SCHEMBL7394534 | 0.77 | CYP1A2 (0.47) | MMP3NPC1RAB9AMEN1CYP3A4 | |
| SCHEMBL7398378 | 0.75 | CYP3A4 (0.46) | MMP3MEN1CYP3A4KMT2AKDM4E | |
| SCHEMBL17509445 | 0.74 | CYP3A4 (0.49) | MEN1CYP3A4KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7991703 | 0.71 | MMP3 (0.43) | MMP3NPC1RAB9AMEN1CYP3A4 | |
| SCHEMBL9419949 | 0.70 | CA1 (0.56) | NPC1RAB9AMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |