Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 5/20 | 0.79 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996909 | 0.88 | MMP3 (1.00) | MMP3NPC1RAB9APDE4BKMT2A | |
| SCHEMBL7990504 | 0.83 | MMP3 (1.00) | MMP3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7990513 | 0.79 | MMP3 (0.67) | MMP3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7996980 | 0.75 | MMP3 (0.69) | MMP3MTNR1AHDAC8HDAC1MAPT | |
| SCHEMBL1303471 | 0.74 | NPC1 (0.85) | NPC1RAB9APDE4BKMT2AHDAC8 | |
| SCHEMBL3223372 | 0.74 | BID (0.50) | KMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL7713404 | 0.73 | BID (0.49) | KMT2AMEN1 | |
| SCHEMBL9256709 | 0.73 | BID (0.56) | KMT2AMEN1MAPT | |
| SCHEMBL28650296 | 0.73 | RAB9A (0.82) | NPC1RAB9APDE4BKMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL7713405 | 0.73 | BID (0.49) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |